Enzyme/Cell Libraries
Your biological diversity. Yeast, bacteria, mammalian cells, or cell-free systems. We work with what you have.
Unlock Enzyme Potential 100x Faster with Ultrahigh-Throughput Screening
Screen 100,000 variants in a single day using label-free mass spectrometry. No more bottlenecks. No more compromises.
You've Solved Design • You've Solved Build • Now Solve Testing
Computational biology and DNA synthesis have evolved exponentially. You can design billions of enzyme variants. But testing them? You're still using 60-year-old microwell plate robotics—screening hundreds per cycle, taking weeks to complete a single optimization round.
The result: Promising leads get shelved. Parallel engineering campaigns become economically unfeasible. Time-to-market suffers.
µMaldi changes that equation.
Traditional
96–384 samples per run. Weeks of analysis. High equipment cost.
µMaldi
100,000 samples per run. Hours of analysis. Benchtop footprint.
Simple Inputs • Transformative Scale
You focus on your science. We handle the platform. Send us your library, substrates, and target outcome.
Substrates & Cofactors
Your chemical precursors. Fatty acids, amino acids, sugars, small molecules—whatever your pathway needs.
Target Outcome
Your goal. Optimize activity? Reduce byproducts? Discover novel reactivity? Define success on your terms.
Comprehensive Data • Immediate Insights
Every variant tells a story. µMaldi doesn't just identify hits—it reveals the full chemical landscape of your library. Full spectral resolution. Unexpected side-reactions. Activity clusters.
High-Performing Mutants
Ranked sequences of your top producers.
Full Spectral Profiles
Complete mass spectrometry data for every variant.
Cluster Analysis
UMAP visualizations separating populations.
Kinetic Data
Substrate selectivity and turnover rates.
Proven Performance Across Multiple Applications
Optimize Industrial Biocatalysts
Maximize catalytic rates, substrate range, and thermostability for commodity chemicals and pharma intermediates.
Access Rare Natural Products
Engineered Cannabis sativa pathways to produce rare cannabinoids with 4x improved efficiency.
Engineer Whole-Cell Biocatalysts
Screen entire metabolic pathways. Identify bottlenecks and discover novel pathway variants.
Ready to Accelerate Your Discovery?
µMaldi is now accepting inquiries for pilot projects and early-access partnerships.